NAS1 — Phaseolus vulgaris

Summary

PHAVU_006G117300, designated PvNAS1 on chromosome 6 of French bean (Phaseolus vulgaris), encodes a nicotianamine synthase, an enzyme with nicotianamine synthase activity that belongs to the SAM-dependent methyltransferase superfamily. The gene is associated with nicotianamine anabolism, nitrogen fixation, phloem transport, pollen tube growth, pollen development, and the response to zinc. It has been linked to cadmium tolerance, iron translocation, chlorosis, iron deficiency tolerance, and rRNA gene expression. Related genes in other species connect the family to iron and zinc homeostasis, iron transport, and cadmium detoxification, while work in tobacco links it to chlorotic leaves, altered metal content, and increased iron uptake.