ALS — Oryza sativa Indica Group

Summary

BGIOSGA015196 (OiALS) on chromosome 4 of Indica rice encodes an acetolactate synthase large subunit, a thiamine pyrophosphate-dependent enzyme. The protein possesses acetolactate synthase, pyruvate decarboxylase and 2-hydroxyacyl-CoA lyase activities, binds TPP, FAD and magnesium, and localises to the chloroplast stroma as part of the acetolactate synthase complex. OiALS is associated with branched-chain amino acid, valine and fatty acid alpha-oxidation metabolism, and with syngamy. The gene is linked to response to herbicide, and specific alleles are connected to imidazolinone herbicide tolerance, herbicide tolerance, aluminum resistance, and aluminium tolerance. Studies of related genes in other species further connect ALS to herbicide resistance, plant growth, tillering, grain yield and drought tolerance.