MYB3 — Nicotiana attenuata

Summary

A4A49_31927 (MYB3/MYB4) on coyote tobacco chromosome 3 encodes a Myb-domain transcription factor with DNA-binding, protein-dimerization and small-GTPase-binding activities. It is associated with regulation of flavonoid, anthocyanin, proanthocyanidin, phenylpropanoid and cinnamic-acid metabolism, as well as trichome differentiation and spacing, herbivore resistance and anti-herbivore defence. The gene is linked to responses to herbivory, oviposition, iron-ion starvation, UV-B light, osmotic and oxidative stress, and low temperature. Associations include leaf trichome density, flavonoid and anthocyanin content, jasmonic-acid and brassinosteroid levels, flowering time, seed and embryo development, root and shoot meristem development, pollen fertility, disease tolerance, salt and freezing tolerance, and plant growth traits. The product localises to the nucleus, cytoplasm and root hair. Studies of related genes in other species link the family to UV-B tolerance, sinapate-ester production, lignin content, pathogen resistance and ABA responses.