LOX — Nicotiana attenuata

Summary

A4A49_32174 (NaLOX) on chromosome 11 of coyote tobacco encodes a lipoxygenase enzyme with linoleate 9S- and 13S-lipoxygenase activity, phytoene dehydrogenase activity, and peroxidase activity. It is associated with the lipoxygenase pathway, oxylipin and jasmonic acid biosynthesis, carotenoid and chlorophyll breakdown, and responses to herbivory and stress. The gene has been linked to green leaf volatile production, wound response, and defense against herbivory. Associations include leaf necrosis, seed yield, plant height, photosynthetic rate, and low temperature stress response. The product localises to chloroplast thylakoids, stromules, P bodies, and stress granules. Studies of related genes in other species link it to jasmonate biosynthesis, resistance to herbivory and necrotrophic pathogens, and stomatal closure.