ACL — Nicotiana attenuata

Summary

A4A49_32727 (ACL, also known as SABP2) in coyote tobacco (Nicotiana attenuata) encodes a protein of the MES/HNL family with alpha/beta hydrolase domains. The enzyme exhibits aliphatic and aromatic (S)-hydroxynitrile lyase, mandelonitrile lyase, polyneuridine-aldehyde esterase, and MESA, MeJA, and MeIAA esterase activities. It is associated with defense response to insects, systemic acquired resistance via salicylic acid-mediated signaling, jasmonic acid and salicylic acid metabolism, indole alkaloid and alkaloid anabolism, nicotinate metabolism, glycoside breakdown, oxylipin anabolism, lipogenesis, gluconeogenesis, fatty acid elongation, the MVA pathway, detoxification, response to UV-B, immune response, and homeostasis. The protein localizes to the vacuole, cytosol, plasmalemma, cytoplasm, and nucleus. The gene is also linked to photosynthetic rate, chlorophyll content, fruit volatile profiles, NAD biosynthesis, seed germination, chilling tolerance, and nicotinate transport.