PAT — Nicotiana attenuata

Summary

A4A49_33897 (PAT, also known as UBQ12) on chromosome 2 of coyote tobacco (Nicotiana attenuata) encodes a protein containing ubiquitin and ubiquitin-like domains, with annotated molecular functions including histone methylase activity, thiol-dependent deubiquitinase activity, structural constituent of ribosome, and protein tag. The gene is associated with modification-dependent proteolysis, deubiquitination, regulation of abscisic acid anabolism, cellular response to salicylate stimulus, and activation of defense response to bacteria. It has been linked to numerous traits including leaf chlorophyll content, biomass yield, plant height, flowering time, seed dormancy, pollen fertility, root mass density, leaf necrosis, temperature stress responses, disease tolerance, and salt tolerance. Localization evidence connects the product to the ESCRT I complex, endosomes, chromosomes, ribosomes, and the ER membrane. Related genes in other species link the family to chilling tolerance, immune response, and nitrogen remobilization.