RPS2 — Nicotiana attenuata

Summary

A4A49_34115 (RPS2) in coyote tobacco (Nicotiana attenuata) on chromosome scaffold01647 encodes a plant NBS-LRR protein with NB-ARC, leucine-rich repeat, and P-loop NTPase domains, and exhibits DPNase, NADP nucleosidase, and ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase activities. It is associated with defense responses to other organisms, including antiviral and antifungal responses, as well as upregulation of programmed cell death, hypersensitive response (HR-PCD), calcium signaling, NAD breakdown, plastid translation, and signal transduction. The gene product localizes to the membrane, plasmalemma, cytoplasm, and nucleus. Related genes in other species link the family to bacterial disease response.