AOX1 — Nicotiana attenuata

Summary

A4A49_29713 (AOX1) in coyote tobacco (Nicotiana attenuata) encodes an alternative oxidase, a mitochondrial enzyme with ubiquinol:oxygen oxidoreductase and alternative oxidase activities, and is also associated with superoxide-generating NADPH oxidase activity and metal binding. The gene is linked to alternative respiration, the electron transport chain, the TCA cycle, and response to oxidative stress, as well as cell death, programmed cell death, cell division, signal transduction, and defense response. It localizes to the mitochondrial inner membrane and respirasome. AOX1 is associated with photosynthetic rate, chlorophyll content, and plant height. Studies of related AOX family members in other species further link the family to these respiratory and stress-associated processes.