PCS1 — Nicotiana attenuata

Summary

A4A49_30011 (PCS1) in coyote tobacco (Nicotiana attenuata) encodes an aspartic endopeptidase, belonging to the pepsin-like plant aspartic peptidase A1 family. The gene is associated with phytochelatin anabolism, cellular detoxification, and response to cadmium, as well as regulation of programmed cell death, hypersensitivity, and cell death. It is also linked to response to vitamin C, response to light stimulus, cellular response to hypoxia, and homeostasis. The encoded protein is localized to the Golgi complex and extracellular region. PCS1 has been connected to increased ABA response and decreased hypoxia tolerance. Studies of related genes in other species link the family to oxidative stress response.