MLO — Nicotiana attenuata

Summary

A4A49_29761, designated MLO5 in Nicotiana attenuata on chromosome 10, encodes a calmodulin-binding protein localized to the plasma membrane, endomembrane system, cytoplasm, nucleus, and mitochondria. The gene is associated with pollen tube reception and guidance, regulation of secondary metabolite biosynthesis including nicotine and alkaloid anabolism, salicylic acid anabolism, auxin transport, response to hormone and stress, metabolic burst, NO storage, homeostasis, RNA breakdown, protein processing and localization, and regulation of growth. It is linked to shoot dry weight and drought tolerance. Studies of related MLO family members in other species connect the family to powdery mildew resistance, defective pollen tube guidance, reduced fertility, and calcium signaling.