NP1 — Nicotiana attenuata

Summary

A4A49_09298 (NP1, NPK1) in coyote tobacco (Nicotiana attenuata) encodes a mitogen-activated protein kinase kinase kinase (MAPKKK) with protein serine/threonine kinase activity, classified as EC 2.7.11.25. The gene is associated with MAPKKK and MAPK binding, as well as sucrose:proton symporter activity and microtubule motor activity. It has been linked to cell signaling, cell proliferation, and oxidative stress tolerance, and to biological processes including lateral growth, regulation of cytokinesis, male meiosis cytokinesis, embryo sac cellularization, sucrose transport, and microtubule-based movement. The product localizes to the microtubule organizing center, plasmalemma, cytoplasm, vacuole, apoplast, nucleolus, plasmodesma, and mitochondria. Associations with traits such as total soluble sugar content, cellulose content, root number, anthocyanin content, drought tolerance, and stomatal opening have been noted. Related genes in other species are linked to cell division, plant immunity, and stress tolerance.