SR1 — Nicotiana attenuata

Summary

A4A49_09673 (NaSR1, also known as SR1 or SRH1) in coyote tobacco (Nicotiana attenuata) on chromosome 1 encodes a RING-HC zinc-finger protein of the ZNF598/HEL2 family with ubiquitin ligase activity (EC 2.3.2.27). The product binds ribosomes, mRNA, transcription cis-regulatory regions, proteins, and zinc, and localises to both the cytoplasm and nucleus. The gene is associated with reactive oxygen species and hydrogen peroxide biosynthesis, pH reduction, response to flooding, cytokinin metabolism, exocytosis, pigmentation, anthocyanin metabolism and its regulation, pistil and flower development, embryogenesis, regeneration, digestion, detoxification, membrane transport, and rescue of stalled cytosolic ribosomes. It is linked to increased oxidative stress sensitivity. Related genes in other species are associated with submergence tolerance and self-incompatibility.