NP1 — Nicotiana attenuata

Summary

A4A49_06228 (NP1, NPK1) in Nicotiana attenuata encodes a mitogen-activated protein kinase kinase kinase (MAPKKK) with MEKK activity, protein serine/threonine kinase activity, and MAPKK binding. It is associated with cell signaling, cell proliferation, and oxidative stress tolerance. The gene is linked to lateral growth, cytokinesis regulation, microtubule organization, and male and female gametogenesis. Associations include defense response, jasmonic acid accumulation, plant immunity, and cell wall integrity. It has been connected to drought tolerance, anthocyanin content, total soluble sugar content, cellulose content, root number, and root thickness. Localization evidence places the product in the cytoplasm, plasmalemma, vacuole, apoplast, nucleolus, plasmodesma, and mitochondria. Related genes in other species link the family to sucrose transport, phloem loading, and cold acclimation.