PNH — Nicotiana attenuata

Summary

A4A49_04981 (PNH/PHN1) in coyote tobacco (Nicotiana attenuata) on chromosome 6 encodes a protein with Argonaute, Piwi, PAZ and RNaseH-like domains, and is annotated with diverse molecular functions including dsRNA binding, siRNA binding, RNA endonuclease activity, histone ubiquitin ligase and deubiquitinase activities, superoxide dismutase activity, and MAP kinase scaffold activity. The gene is associated with miRNA and siRNA metabolic processes, gene silencing by miRNA-directed mRNA cleavage, regulation of epidermis development, somatic stem cell population maintenance, temporal regulation of development, and regulation of secondary metabolism and flavonoid anabolism. It is linked to competitive growth, leaf polarity and morphology, auxin signalling, TAS3 ta-siRNA biogenesis, juvenile-to-adult transition, virus resistance, and traits including photosynthetic ability, root phototropism, UV light sensitivity, lignin biosynthesis, inflorescence development, and seed dormancy.