SR1 — Nicotiana attenuata

Summary

A4A49_05680 (SR1, also known as CMTA3) in coyote tobacco (Nicotiana attenuata) encodes a calmodulin-binding transcription activator containing CG-1, ankyrin repeat and IQ motif domains, and is annotated as a DNA-binding transcriptional co-regulator. The gene is associated with diverse biological processes including cellular response to aluminum, reactive oxygen species and hydrogen peroxide biosynthesis, cytokinin metabolism, pigmentation, anthocyanin regulation, pistil development, cold and freezing responses, exocytosis, extracellular ATP signaling, and upregulation of defense responses to insects. It localizes to the nucleus, cytoplasm and extracellular space. SR1 is linked to numerous traits including anthocyanin and carotenoid content, seed size, flowering time, root development, leaf senescence, and responses to temperature, salt and aluminum stress. Studies of related genes in other species connect the family to immunity, salicylic acid pathway regulation, cold tolerance and pathogen resistance.