ADC — Nicotiana attenuata

Summary

A4A49_04912 (ADC, SPE1) on chromosome 1 of coyote tobacco (Nicotiana attenuata) encodes an arginine decarboxylase (EC 4.1.1.19) with protein homodimerization and binding activities, belonging to the Orn/DAP/Arg decarboxylase family. The gene is associated with polyamine, nicotine, alkaloid, and ethylene metabolism, putrescine, spermidine, and spermine biosynthesis, arginine breakdown, and primary and secondary metabolism. It is linked to flower and callus formation, organogenesis, chewing response, virus-induced PTGS, and heterosis. Associations include leaf chlorosis, photosynthetic rate, root meristem size, iron deficiency and salt tolerance, bacterial disease resistance, cold tolerance, seed germination, leaf and root development, plant height, flowering time, wound response, and abiotic stress responses. The protein localizes to the cytosol and nucleus. Studies of related genes in other species link the family to drought tolerance, polyamine content, root architecture, freezing tolerance, and disease resistance.