SKP1 — Medicago truncatula

Summary

MTR_8G089730, the SKP1 gene on barrel medic (Medicago truncatula) chromosome 8, encodes a member of the SKP1 protein family, which includes the SKP1-like dimerisation and BTB/POZ domains and is associated with cullin family protein binding. The gene is associated with protein ubiquitination, particularly SCF-dependent proteasomal ubiquitin-dependent protein breakdown, and with cell cycle, cell division, cell motility, secretion, and homeostasis. It has been linked to jasmonic acid (JA) signalling, as well as organ growth, leaf development, and flower development. Associations with leaf size have also been noted. The encoded protein localises to both the cytoplasm and the nucleus. Studies of related genes in other species further connect the SKP1 family to these processes.