CYP716A1 — Medicago truncatula

Summary

MTR_8G100135, also known as CYP716A12, CYP716A1 or CYP716A2, encodes a cytochrome P450 with beta-amyrin 28-monooxygenase activity, an iron- and heme-binding oxidoreductase that acts on paired donors with incorporation of molecular oxygen. In barrel medic (Medicago truncatula) on chromosome 8, this gene is associated with pentacyclic triterpenoid, triterpenoid, sterol, saponin and secondary metabolism, as well as triterpenoid and saponin biosynthesis and electron transfer. The encoded product localises to membranes and the extracellular region. Leaf necrosis has been linked to this gene. Studies of related genes in other species connect the family to beta-amyrin 28-oxidase activity and various climate-associated phenotypes, though these relationships are not established for MTR_8G100135 itself.