ADH — Medicago truncatula

Summary

MTR_8G095220 (symbol ADH, preferred name MtHER2) on barrel medic chromosome 8 encodes a protein with S-(hydroxymethyl)glutathione dehydrogenase activity (NAD+, NADP+, and NAD(P)+), aldo-keto reductase (NAD) activity, and binding sites for cobalt and zinc. The protein contains ADH-like and GroES-like domains and is localized to plastids, mitochondria, and cytosol. This gene is associated with response to alcohol, methanal catabolism, the shikimate pathway, alkaloid metabolism, and response to AOS. It has been linked to pollen fertility, germination rate, and E-2-hexenal responsiveness. Studies of related genes in other species connect the family to traits including drought tolerance, submergence tolerance, root volume, plant height, seed size, seed maturation, and nitrogen, proline, and protein content, as well as reduced root growth inhibition by E-2-hexenal.