CDKF-3 — Medicago truncatula

Summary

MTR_8G012450 (CDKF-3) on chromosome 8 of barrel medic encodes a protein with cyclin-dependent kinase activity, RNA polymerase II CTD heptapeptide repeat kinase activity, protein serine kinase activity, protein serine/threonine kinase activity, and ATP binding, belonging to the MAPK and protein kinase domain families. The gene is associated with cell cycle regulation, including G1/S transition, mitotic and meiotic cell cycle modulation, and regulation of mitotic entry, as well as cell division, differentiation, development, organogenesis, leaf development, and nodulation. It is linked to intracellular signal transduction, regulation of gene expression, protein synthesis, nitrate import, nitric oxide storage, cell motility, and traits including nitrate uptake, root length, and plant height. The encoded protein localises to the cytoplasm, nucleus, and CDK holoenzyme complex. Studies of related genes in other species link the family to cyclin-dependent kinase activity (EC 2.7.11.22 and 2.7.11.23).