CYP — Medicago truncatula

Summary

MTR_8G036015 (CYP, MtCYP18-1) on barrel medic chromosome 8 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cyclophilin-like domains. The gene product possesses cis-trans proline isomerase activity, binds cyclosporin A, U2 and U5 snRNAs, and proteins. It is associated with protein folding, regulation of protein refolding, mRNA splicing via the spliceosome, electron transfer, triterpenoid anabolism, and shoot development. MtCYP18-1 is linked to responses to abscisic acid, salt, mannitol, heat, and activation of salinity response. It localises to the cytoplasm, nucleus, nucleolus, chloroplast stroma, stress granules, and plasmalemma. The gene is associated with leaf necrosis, heat stress tolerance, heat stress response, and pre-mRNA splicing. Studies of related genes in other species link the family to high temperature stress response.