CYP — Medicago truncatula

Summary

MTR_8G040180 (symbol CYP) in barrel medic (Medicago truncatula) chromosome 8 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cyclosporin A binding and cis-trans proline isomerase activity. The gene is associated with protein folding, regulation of protein refolding, electron transfer, triterpenoid anabolism, shoot development, and responses to abscisic acid, salt, and mannitol, including activation of the salinity response. It has been linked to leaf necrosis. The encoded protein localises to the plant-type vacuole, chloroplast stroma, cytosol, plasmalemma, cytoplasm, and nucleus. Related genes in other species link the cyclophilin family to peptidyl-prolyl cis-trans isomerase activity (EC 5.2.1.8).