CHS — Medicago truncatula

Summary

MTR_3G083910 (MtCHS) encodes a chalcone synthase, a type III polyketide synthase with chalcone/stilbene synthase domains. The gene product exhibits naringenin-chalcone synthase, chalcone isomerase, dihydroflavanol 4-reductase, flavanone 4-reductase, flavonol synthase, and SUMO transferase activities. MtCHS is associated with chalcone, polyketide, flavonoid, anthocyanin, and phenylpropanoid biosynthesis, as well as regulation of anthocyanin and phenylpropanoid metabolism, auxin polar transport, response to UV-B and gravity, fruit ripening, and sumoylation. The protein localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. MtCHS is linked to seed coat color and pigmentation, anthocyanin content, drought tolerance, salt stress tolerance, root-knot nematode resistance, flowering time, and stomatal opening. Studies of related genes in other species connect the family to flavonoid production, UV-B sensitivity, and male fertility.