CHS — Medicago truncatula

Summary

MTR_3G088670 (CHS) on barrel medic chromosome 3 encodes a protein with chalcone/stilbene synthase, polyketide synthase type III, and thiolase-like domains. The gene is annotated with naringenin-chalcone synthase and acridone synthase activities, as well as acyltransferase and protein homodimerization activities. CHS is associated with flavonoid, phenylpropanoid, and polyketide anabolism, secondary metabolism, auxin transport, signal transduction, defense response, nodulation, fruit ripening, geotropism, and virus-induced PTGS. The gene product localizes to the endoplasmic reticulum. An association with fruit color has been noted. Related genes in other species, including CHS2, CHS3, CHS8, and trihydroxystilbene synthase, link the family to additional polyketide synthase activities (EC 2.3.1.212, 2.3.1.159, 2.3.1.74).