CHS — Medicago truncatula

Summary

MTR_3G088675 (CHS) in barrel medic (Medicago truncatula) on chromosome 3 encodes a chalcone/stilbene synthase family protein with polyketide synthase type-III domains and exhibits naringenin-chalcone synthase and trihydroxystilbene synthase activities, along with protein homodimerization activity. The gene is associated with flavonoid, chalcone, polyketide, cannabinoid, and phenylpropanoid anabolism, as well as secondary metabolism, auxin transport, signal transduction, defense response, nodulation, geotropism, fruit ripening, pollen wall assembly, and virus-induced PTGS. It localizes to the cytoplasm, endoplasmic reticulum, and PKS complex. The gene has been linked to fruit color. Studies of related genes in other species, including CHS1, CHS2, and CHS4, connect the family to chalcone synthase (EC 2.3.1.74) and trihydroxystilbene synthase (EC 2.3.1.95) activities.