PRO2 — Medicago truncatula

Summary

MTR_3G069080 (PRO2, MtP5CS1) encodes a bifunctional enzyme with glutamate 5-kinase and glutamylphosphate reductase activities, together forming D1-pyrroline-5-carboxylate synthetase. The gene is associated with proline content and accumulation, and has been linked to responses to desiccation, hyperosmotic salinity, oxidative stress, and abscisic acid. Associations also include nitrogen fixation, root development, embryo development, seed germination, and the transition to flowering. Phenotypic links connect it to salt and drought tolerance, freezing tolerance, arsenic tolerance, photosynthetic rate, plant height, flowering time, pollen development and fertility, and root meristem size. The encoded protein localises to the cytoplasm, mitochondria, Golgi complex, and plasmodesmata. Studies of related genes in other species link the family to abiotic stress tolerance, root elongation, and proline biosynthesis.