ATM4 — Lactuca sativa

Summary

LsATM4, also known as ATM4, is a garden lettuce (Lactuca sativa) gene on chromosome 2 that encodes a protein with a Myb domain and SANT/Myb domain, and has DNA binding, transcription factor activity, and protein dimerization activity. It is associated with regulation of flavonoid, proanthocyanidin, phlobaphene, and glucosinolate biosynthetic processes, pigment accumulation in tissues, trichome morphogenesis and spacing, and plant epidermal cell fate specification. The gene is linked to cellular detoxification of cadmium ions, response to sulfur starvation, and defense responses to insects. Associations with traits include leaf trichome density, seed protein content, shoot elongation under submergence, branch angle, phosphorus response, iron concentration, and photoperiod-sensitive flowering time. Studies of related genes in other species link the family to cuticle development, suberin biosynthesis, and drought response.