ANS — Lactuca sativa

Summary

LsANS, encoded by the gene LSAT_V11C200096070 on chromosome 2 of garden lettuce (Lactuca sativa), is a 2-oxoglutarate-dependent dioxygenase with jasmonic acid hydrolase, leucocyanidin oxygenase, flavonol synthase, and flavanone 3-dioxygenase activities. It is associated with anthocyanin, flavonoid, and pigment accumulation, as well as the regulation of jasmonic acid-mediated signaling and defense responses to insects, fungi, and oomycetes. The gene is linked to traits including leaf color, anthocyanin and flavonoid content, chlorophyll content, photosynthetic rate, stomatal resistance, plant width, and shoot dry weight. It has also been connected to drought tolerance, biotic stress tolerance, spider mite resistance, and oxidative stress. Studies of related genes in other species link the family to jasmonic acid response and disease resistance.