HSP70 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.6HG0546450, symbol HSP70, on barley chromosome 6H encodes an ATP-dependent protein folding chaperone with heat shock protein binding and ATP hydrolase activity, belonging to the Hsp70 family and containing a heat shock 70 conserved site and ATPase NBD domain. The gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, response to heat, response to stress, response to virus, immune response, innate immunity, pollen tube growth, lipid metabolism, and response to thirst. Its product localises to the ER chaperone complex, ER lumen, chloroplast membrane, membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species link the family to protein kinase domains.