PAP5 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.6HG0570590 (HvPAP5, also known as HvSAG12) on barley chromosome 6H encodes a papain-like cysteine peptidase belonging to the peptidase C1A family, with thiol endopeptidase and cysteine-type peptidase activity. The gene is associated with leaf senescence, programmed cell death, cell death, and developmental processes including flower and pollen development. It has been linked to responses to abscisic acid, ethylene, and gibberellin, as well as to the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, proteolysis, regeneration, and cell differentiation. The encoded protein localises to the senescence-associated vacuole, lysosome, protein storage vacuole, aleurone body, and ER lumen. Studies of related genes in other species link the family to senescence-associated proteolysis.