PAP5 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.5HG0511140, designated PAP5 and also known as HvSAG12, encodes a papain-like cysteine peptidase with thiol endopeptidase activity. This barley gene on chromosome 5H is associated with leaf senescence, a trait directly annotated on it, and with programmed cell death, cell death, and developmental processes. It is linked to proteolysis and protein breakdown, as well as responses to the hormones abscisic acid, ethylene, and gibberellin. The encoded product localises to senescence-associated vacuoles, protein storage vacuoles, lysosomes, and the ER lumen. Studies of related genes in other species connect the family to cysteine-type peptidase activity.