ERD2 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.5HG0441860 (HvERD2) on barley chromosome 5H encodes a member of the Hsp70 family of ATP-dependent protein folding chaperones, containing the characteristic heat shock 70 kDa protein domain and ATPase nucleotide-binding domain. The encoded protein is associated with diverse molecular functions including calcium-dependent phospholipid binding, D-glucose binding, preprotein binding, protease binding, Hsp90 binding, poly-A binding, and double-stranded methylated DNA binding. It is linked to numerous biological processes such as protein folding in the endoplasmic reticulum, chaperone-mediated protein complex assembly, RuBisCO assembly, mitochondrial matrix protein import, cytosol-to-ER transport, protein localization to chloroplasts, cellular response to salicylate stimulus, and upregulation of defense responses to oomycetes. Associations with agronomically relevant traits include grain filling period, biomass yield, photosynthetic ability, carotenoid content, reproductive and vegetative growth time, leaf and inflorescence morphology, chloroplast development, cell cycle and elongation traits, and responses to light intensity, humidity, chlorate, and various hormones including auxin, gibberellic acid, ethylene, and brassinosteroids. The gene is also linked to stress responses including temperature, salt, chilling tolerance, pathogen resistance, and herbivory resistance.