ADH — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.3HG0252910 (HvADH) on barley chromosome 3H encodes an alcohol dehydrogenase with S-nitrosoglutathione reductase, S-(hydroxymethyl)glutathione dehydrogenase, and aldo-keto reductase activities. The gene is associated with ethanol fermentation, activation of cellular response to hypoxic stress, methanal metabolism, pyruvate metabolism, and cellular respiration. It has been linked to grain yield, grain dry weight, seed size, protein content, photosynthetic rate, respiration rate, drought tolerance, submergence tolerance, waterlogging tolerance, hypoxia tolerance, cold stress tolerance, herbicide sensitivity, disease tolerance, and salt stress response. The product localizes to the cytosol, plastid, mitochondria, nucleus, and plasmalemma. Studies of related genes in other species link the family to hypoxia response, freezing tolerance, drought resistance, and cadmium tolerance.