HSP70 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.2HG0203560 (HSP70) on barley chromosome 2H encodes a heat shock 70 family chaperone with ATP hydrolase activity and ATP-dependent protein folding chaperone function. It is associated with protein refolding, the ERAD pathway, and the unfolded protein response, as well as responses to heat, stress, and virus infection. The gene has been connected to immune response, innate immunity, pollen tube growth, and lipid metabolism. Its product localises to the ER lumen and chaperone complex, chloroplast membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species link the family to similar chaperone and stress-response roles.