MLO — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.2HG0209210, the barley MLO gene on chromosome 2H, encodes a calmodulin-binding protein that localises to the plasma membrane, endomembrane system, Golgi, plasmodesmata, root hairs and cytoplasm. It is associated with host invasion, invasive growth, cell polarization, endosomal transport, pollen tube reception and guidance, metabolic burst, protein polyubiquitination, virus-induced PTGS, vesicle transport, downregulation of defense response, immune response and response to fungi. The gene is linked to leaf necrosis, leaf chlorosis, grain yield, root gravity response, Botrytis cinerea resistance, leaf senescence, callose deposition, systemic acquired resistance, root thigmomorphogenesis and pollen. Studies of related genes in other species connect the family to powdery mildew resistance, disease susceptibility, ozone tolerance, calcium signaling, cell death, pollen hydration and fertilization.