PAP5 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.2HG0103440 (HvPAP5, also known as HvSAG12) on barley chromosome 2H encodes a papain-like cysteine peptidase of the C1A family, with thiol endopeptidase activity and proteinase-activated receptor binding. The gene is associated with programmed cell death, floral organ senescence, and proteolysis, and its product localises to senescence-associated vacuoles, lysosomes, and the ER lumen. HvPAP5 is linked to leaf senescence, seed yield, nitrogen remobilisation, drought resistance, and flooding tolerance. It is associated with responses to multiple hormones (auxin, cytokinin, ethylene, gibberellin), sugars (fructose, glucose, sucrose), UV-B, and fungal defence, as well as the MVA and MEP pathways. Related genes in other species are linked to developmental senescence, cadmium-induced programmed cell death, and saccharification efficiency.