PAP5 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.2HG0103460 (HvPAP5, also known as HvSAG12) on barley chromosome 2H encodes a papain-like cysteine peptidase belonging to the peptidase C1A family, with thiol endopeptidase activity and protein binding capability. The gene is associated with programmed cell death during development, floral organ senescence, and proteolysis, and is linked to responses to multiple hormones including ethylene, cytokinin, auxin, and gibberellin, as well as to sugars such as glucose, fructose, and sucrose. It has been connected to leaf senescence, seed yield, nitrogen remobilization, seed nitrogen content, drought resistance, and flooding tolerance. The encoded protein localizes to senescence-associated vacuoles, lysosomes, protein storage vacuoles, and the ER lumen. Related genes in other species are linked to developmental senescence and cadmium-induced programmed cell death.