ALS — Glycine max

Summary

GmALS (GLYMA_06G169700V4) on soybean chromosome 6 encodes the large subunit of acetolactate synthase (ALS), a thiamine pyrophosphate-dependent enzyme. The gene product possesses acetolactate synthase, pyruvate decarboxylase and 2-hydroxyacyl-CoA lyase activities, binds TPP, FAD and magnesium, and localises to the chloroplast stroma as part of the acetolactate synthase complex. GmALS is associated with response to herbicide, salt stress, nitrogen fixation, nodulation, photorespiration, secondary metabolism and lipid metabolism. The gene has been linked to seed weight, plant height, nitrogen content and salt tolerance. A specific G121A variant is associated with herbicide tolerance. Studies of related genes in other species connect it to herbicide resistance, imidazolinone and sulfonylurea sensitivity, and plant growth and seed production.