MUP1 — Fusarium graminearum PH-1

Summary

FgMUP1 (FGRAMPH1_01G05167) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein belonging to the amino acid transporter family, specifically the AA/rel_permease1 subfamily. The gene is associated with sporulation and morphogenesis based on ontology annotations. Numerous phenotypic associations have been linked to this gene, including alterations in protein transport, endocytosis, cell cycle progression, nutrient uptake, and vegetative growth. It is also associated with changes in stress responses, such as increased resistance to hydrostatic pressure and alkaline pH, as well as decreased cold sensitivity. Additionally, FgMUP1 is associated with apoptosis, mitophagy, and mutation frequency. Studies of related genes in other species link the family to methionine permease activity and oxidative stress response, though these functions are not established for FgMUP1 itself.