AP2A1 — Daucus carota subsp. sativus

Summary

DCAR_015485, designated DcAP2A1 on carrot chromosome 4, encodes a large subunit of the AP-2 clathrin adaptor complex, possessing clathrin adaptor, phospholipid-binding and structural molecule activities. The gene is associated with clathrin-mediated endocytosis, auxin polar transport and export across the plasma membrane, and positive gravitropism. It has been linked to root branching, lateral root number and length, root hair length, root thickness, root mass density, biomass yield, phototropism, temperature stress response, aluminum response, ethylene sensitivity, self-incompatibility, and disease tolerance. The encoded protein localises to the clathrin adaptor complex, basal plasma membrane, cell plate, Golgi, trans-Golgi network, lytic vacuole, and stress granules. Studies of related genes in other species link the family to polar subcellular localisation, root growth direction, cell elongation, biomass production, and root circumnutation.