M2 — Daucus carota subsp. sativus

Summary

DCAR_014670, symbol DcM2 on carrot chromosome 4, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase, EC 5.2.1.8) with cyclosporin A binding and cis-trans proline isomerase activity. The gene is associated with protein folding and regulation of protein refolding, as well as responses to abscisic acid, salt, and mannitol. It is linked to activation of the salinity response, sensitization, and carotenoid anabolism. The product localises to the chloroplast stroma, cytosol, cytoplasm, nucleus, and plasmalemma. Studies of related genes in other species link the family to general PPIase and CYP functions, but these associations are not yet established for DcM2 itself.