NHX1 — Cucumis sativus

Summary

CsNHX1 (CSA_1G573610) on cucumber chromosome 1 encodes a member of the cation/H⁺ exchanger (CPA1) family, specifically a Na⁺/H⁺ exchanger with lithium:proton and potassium:proton antiporter activity, sodium transporter activity, and additional annotated functions including NAD ADP-ribosyltransferase and protein kinase activities. The protein localises to the tonoplast, vacuolar membrane, endosomes, and plastid envelopes, and is associated with vacuolar membrane transport, sodium and potassium ion homeostasis, cell pH regulation, brassinosteroid and nitric oxide anabolism, and responses to superoxide. CsNHX1 has been linked to sodium exclusion, yield traits, plant height, root development, chlorophyll content, photosynthetic rate, stomatal resistance, and tolerance to high temperature, drought, and disease. Related genes in other species connect this gene family to vacuolar pH regulation, potassium accumulation, heat and cold tolerance, seed germination, and biomass production.