DNAJ1 — Cucumis sativus

Summary

CSA_1G642540 (DNAJ1) on cucumber chromosome 1 encodes a DnaJ/Hsp40 family protein with a J domain, cysteine-rich region, and ATPase activator activity that binds Hsp70 and other chaperones. The gene is associated with protein folding in the endoplasmic reticulum, cellular response to heat, protein refolding, and chaperone binding. It has been linked to chlorophyll and carotenoid metabolism, pigment anabolism, stomatal closure, immune response, and fermentation. Associations with agronomic traits include drought tolerance, leaf color, endocarp color, carotene content, chlorophyll content, and abscisic acid content. The protein localizes to the ER lumen, membrane, cytosol, plasmalemma, cytoplasm, and nucleus. Studies of related genes in other species connect the family to stress responses and protein homeostasis.