IRT1 — Cucumis sativus

Summary

CSA_1G707110 (IRT1, also known as CsZIP10, IRT2, ZIP10, CsIRT2, CsIRT1) on cucumber chromosome 1 encodes a ZIP family metal transporter with transmembrane transporter activity for copper, manganese, zinc, iron, and cadmium, as well as phosphoinositide and ubiquitin binding. The gene is associated with metal ion transport, cellular and multicellular iron homeostasis, cadmium detoxification and accumulation, zinc accumulation, iron deficiency tolerance and response, plant growth promotion, photosynthetic efficiency, chlorophyll content, chloroplast development, root and lateral root development, leaf development, disease resistance, and induced systemic resistance. It is also linked to auxin and ethylene anabolism, auxin transport, MVB formation, endosome membrane budding, and regulation of cellular response to basic pH. The protein localizes to the plasma membrane, late endosome membrane, ESCRT I complex, trans-Golgi network, endosome, and nucleus.