ASD — Cucumis sativus

Summary

CsASD (CSA_1G168880) on cucumber chromosome 1 encodes a TASSELSEED2-like protein belonging to the short-chain dehydrogenase/reductase (SDR) family, with NAD(P)-binding and oxidoreductase activity acting on CH-OH donors. The enzyme exhibits multiple annotated activities including momilactone-A synthase, zerumbone synthase, (+)-borneol dehydrogenase, secoisolariciresinol dehydrogenase, and xanthoxin dehydrogenase (NAD+) activities, as well as aldo-keto reductase activity. CsASD is associated with sex determination, abscisic acid and gibberellic acid signaling, chlorophyll breakdown, response to UV and jasmonic acid, seed germination, sulfation, and biosynthesis of terpenoids, phenylpropanoids, lignans, monoterpenoids, and (+)-camphor. The protein localises to mitochondria and cytosol. The gene has been connected to photosynthetic rate, transpiration rate, stomatal resistance, quantum yield, and nitrate uptake. Studies of related genes in other species link the family to alcohol dehydrogenase and secoisolariciresinol dehydrogenase activities.