HMA1 — Cucumis sativus

Summary

CSA_1G423340, symbol HMA1 and also known as HMA4, encodes a P-type ATPase with heavy-metal-associated domains, annotated with copper, zinc, and cadmium transmembrane transporter activities as well as histone methylase activity. In cucumber, this gene is associated with detoxification of zinc, copper, and cadmium ions, copper and zinc homeostasis, response to cobalt and toxic substances, and processes including isoleucine breakdown, ALA metabolism, proton export, and cell pH regulation. It has been linked to traits such as copper sensitivity, drought tolerance, chlorophyll content, plant height, flowering time, leaf senescence, stomatal opening, and bacterial disease response. Studies of related genes in other species connect the family to heavy metal tolerance, cadmium translocation, zinc homeostasis, and copper transport, as well as to photosynthetic performance under high light.