PNH — Cucumis sativus

Summary

CsPNH (CSA_1G408710) on cucumber chromosome 1 encodes a Piwi domain-containing protein with Argonaute family domains, including Piwi, PAZ-like and RNaseH-like folds, and is annotated with diverse molecular functions such as siRNA binding, RNA endonuclease activity, histone ubiquitin ligase and deubiquitinase activities, and DNA-binding transcription activator activity. The gene is associated with miRNA and tasiRNA metabolic processes, somatic stem cell maintenance, gene silencing by miRNA-directed mRNA cleavage, and regulation of development and body size. It has been linked to numerous traits including leaf morphology and polarity, male flowering, flower abscission, fruit position, seed viability and dormancy, photosynthetic ability, root phototropism, and responses to UV light. Studies of related genes in other species connect the family to leaf shape, virus resistance, auxin signalling, juvenile-to-adult transition, and reproductive development.