CHS — Cucumis melo

Summary

MELO3C017129.2 (CmCHS) on melon chromosome 3 encodes a protein with chalcone/stilbene synthase and type III polyketide synthase domains. The enzyme is annotated with naringenin-chalcone synthase, chalcone isomerase, flavanone 4-reductase, flavonol synthase, and tetraketide alpha-pyrone synthase activities. CmCHS is associated with chalcone, polyketide, flavonoid, anthocyanin, and phenylpropanoid biosynthesis, as well as pollen wall assembly, fruit development and ripening, wound healing, UV-B response, auxin polar transport, and sumoylation. The protein localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. CmCHS is linked to anthocyanin content, photosynthetic and respiration rates, flowering time, root morphology, stomatal opening, and responses to UV light, salt, drought, oxidative stress, and root-knot nematodes. Studies of related genes in other species connect the family to male fertility, pollen exine formation, seed coat pigmentation, and disease resistance.