M2 — Cucumis melo

Summary

MELO3C018433.2, also known as CmM2, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) on melon chromosome 2. The product possesses domains characteristic of cyclophilins and tetratricopeptide repeats, and is annotated with cis-trans proline isomerase activity, as well as binding activities for cyclosporin A, salicylic acid, histones, and chromatin. In melon, CmM2 is associated with diverse biological processes including protein proline isomerization, regulation of ARF protein signal transduction, response to light intensity and sulfate starvation, basipetal auxin transport, and alternative mRNA splicing. The gene is linked to numerous agronomic traits such as variegated leaf, starch grain synthesis, respiration and photosynthetic rates, sucrose content, root hair length, meristem identity, chloroplast development, jasmonic acid content, and responses to temperature stress, arsenic, and herbicides. Studies of related genes in other species connect the family to heat stress tolerance, pre-mRNA splicing, hydrotropism, phototropism, embryo patterning, and drought response.