TBP2 — Cucumis melo
Summary
MELO3C018014.2, also known as CmTBP2, encodes a protein with TBP-class protein binding, double-stranded telomeric DNA binding, and DNA binding transcription factor activity, containing Histone_H1/H5_H15 and WH-like DNA-binding domains. In melon, this gene is associated with fruit development and ripening, telomere maintenance and its positive regulation via telomerase, nucleosome assembly, DNA damage response, and cellular response to UV-C. It is linked to disease tolerance and root morphology traits, as well as severe growth defects, small seedlings, and complete infertility. The protein localizes to the nucleus, nucleolus, chromatin, and telomeric regions. Related genes in other species are linked to telomere length regulation and telomeric DNA binding.
Annotations
- Chromosome
- 8
- Related genes
- TBP2, ATPOT1, ETL1, TBP3, TRB1
- GO terms
- telomeric ssDNA binding, Promoter-specific Chromatin Binding, TBP-class Protein Binding, GO:0000786, Fruit Development, DNA-templated Transcription Initiation, Nucleosome Assembly, telomeric repeat binding
- Publications
- 28298478, 26597966, 8643494, 36903861, 17640338, 35560426, 15489532, 14558660
- Traits
- mitochondrial function, mitophagy, H3K4me3 demethylation, other miscellaneous trait, Severe Growth Defects, Small Seedlings, Complete Infertility, Progressive Telomere shortening with Progressive Telomere Shortening, Telomere Shortening Similar to Related Mutants, Telomere Shortening with Failure to Elongate Telomeres